In vitro activities of OPC-17116, a new quinolone; ofloxacin; and sparfloxacin against Chlamydia pneumoniae.
نویسندگان
چکیده
The in vitro susceptibilities of 12 strains of Chlamydia pneumonia to a new quinolone, OPC-17116; ofloxacin; and sparfloxacin were determined. OPC-17116 was slightly less active than sparfloxacin but more active than ofloxacin, with a MIC for 90% of strains tested and a minimal chlamydiacidal concentration for 90% of strains tested of 0.5 micrograms/ml.
منابع مشابه
In Vitro and in Vivo Antibacterial Activity of Four Newly Developed Quinolone Agents against Legionella Infection
We investigated the antibacterial activity of four newly developed quinolone agents, temafloxacin (TMFX, TA-167), sparfloxacin (SPFX , AT -4140) , OPC -17116 and Y 26611 against Legionella was investigated both in vitro and in vivo and compared them with those of other quinolone agents and with erythromycin. In vitro strength of the antibacterial activity was found to be in the order of stronge...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 38 6 شماره
صفحات -
تاریخ انتشار 1994